International Journal of Nursing Research

Objective To investigate the efficacy of precision stratified management in controlling volume load among peritoneal dialysis (PD) patients. Methods Eighty PD patients undergoing regular follow-up at the Department of Nephrology, a Grade III Class A hospital in Shiyan City, Hubei Province, from January to June 2025 were randomly divided into two groups. The control group (n=40) received conventional health management, while the observation group (n=40) received precision stratified management in addition to conventional care. Comparisons were made between the two groups regarding fluid indicators, edema status, knowledge of fluid-related concepts, and fluid management behaviors before and after intervention. Results (1) Before intervention, no statistically significant differences were observed between the two groups in extracellular water (ECW)/total body water (TBW) ratio or N-terminal pro-brain natriuretic peptide (NT-proBNP) levels (P > 0.05). After 6 months of intervention, the ECW/TBW ratio in the observation group decreased from (0.41 ± 0.03) to (0.37 ± 0.02), while NT-proBNP decreased from (12856.45 ± 352.67) pg/mL to (8685.30 ± 150.45) pg/mL, with a significantly greater reduction than in the control group (P < 0.001). (2) After intervention, the incidence of moderate-to-severe limb edema was 15.00% in the observation group and 40.00% in the control group (P < 0.05); (3) Six months after intervention, the observation group’s fluid-related knowledge score increased from (62.35±8.20) to (89.72±5.63), and the fluid management behavior score rose from (42.18±6.35) to (53.42±4.87), both significantly higher than the control group (P<0.05). Conclusion Implementing precision stratified management in fluid management for PD patients improves fluid status, reduces limb edema, and enhances self-management capabilities.

Precision stratified management; Peritoneal dialysis; Fluid management; Application efficacy