Journal of International Psychiatry

【Abstract】 Objective To investigate the effect of levonorgestan on the cognitive function and quality of life in children with refractory epilepsy. Methods A total of 110 children were enrolled in our hospital from 2013.1 to 2016.1 as the study group. 110 normal children were selected as the control group. The quality of life was evaluated in the study group and then compared with the control group. The assessment was based on epilepsy Childrens Quality of Life Scale (QOLCE), children were treated with levetiracetam for 8 months and then evaluated again before comparison with the treatment. Four patients with different types of epilepsy were compared. Results The total effective rates were 90.9%, 93.8%, 85.7% and 85.7%, respectively. The scores of the patients in the study group were significantly higher than those in the control group (P <0.05). (P <0.05). There was a significant difference between the scores before and after treatment (P <0.05), and the score of the scores of the study group was significantly higher than that of the control group (P <0.05) <0.05). Conclusion The use of levetiracetam in the treatment of refractory epilepsy children can effectively improve the childrens cognitive function and quality of life, it is worth promoting the use.

【Key words】Zuo Laxitan;Children; refractory epilepsy;Cognitive function;Quality of Life