| Abstract |
[Abstract] Objective: To study the effect of intensive blood glucose control nursing on blood glucose fluctuation and the incidence of related complications in patients with type 2 diabetes mellitus (T2DM) complicated with schizophrenia. Methods: 94 cases of patients with T2DM complicated with schizophrenia treated in our hospital from January 2015 to August 2016 were enrolled in the study. By the random sampling method, they were divided into two groups, 47 cases in each group. Both groups were given routine treatment and nursing, and the observation group was additionally given intensive blood glucose control nursing. The fluctuation of blood glucose, glycosylated hemoglobin (HbA1C), fructosamine (FMN), C peptide level, calcium binding protein (S100-β), neurotrophin 3 (NT-3), mental nursing observation (NORS) score, compliance and complications were compared between the two groups. Results: After 3 months of treatment, the levels of FPG, 2hPG, HbA1C, FMN and S100-β in the observation group were significantly lower than those in the control group, and the levels of C peptide and NT-3 were significantly higher than those in the control group (P < 0.05). The NORS score of the observation group was lower than that of the control group (P < 0.05), while the compliance rate was significantly higher than that of the control group (59.57% vs 40.43%) (P < 0.05). The total incidence of complications such as microvascular events, hypoglycemia, renal dysfunction and gastrointestinal discomfort in the observation group (6.38%) was lower than that in the control group (29.79%) (P < 0.05). Conclusion: The application of intensive blood glucose control nursing in patients with T2DM and schizophrenia can effectively control the blood glucose level, and improve mental state, improve the treatment compliance and reduce the risk of complications, thus obtaining good prognosis.
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