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【Abstract】 Objective To investigate the clinical effect of psychological counseling combined with flupaphene tromethamine in the treatment of coronary heart disease with anxiety and depression. Methods From October 2015 to April 2017, selected 104 patients with CHD combined with anxiety and depression in Yunnan Province psychiatric hospital hospital were randomly divided into observation group and control group, each group 52 cases. The control group was given conventional treatment of CHD, the observation group was treated with flupapril thalidomide tablets combined with psychological counseling on the basis of the control group. Negative emotions [anxiety(HAMA), depression (HAMD)] scores, treatment compliance, quality of life score and CHD treatment effect before and after treatment, the incidence of adverse reactions during treatment were compared between the two groups. Results (1) Negative mood: HAMA and HAMD scores in the observation group were not significantly different from those in the control group before treatment (P> 0.05), while after treatment, the observation group was lower than the control group, the difference was statistically significant (P <0.05); (2) treatment compliance: the treatment compliance in the observation group was superior to the control group, the difference was statistically significant (P <0.05); (3) CHD clinical efficacy: observation group of clinical efficacy was better than the control group, the difference was statistically significant (P <0.05); (4) Adverse reactions: the incidence of adverse reactions in the observation group [17.31% (9/52) vs 9.62% (5/52)] compared with the control group, the difference was not statistically significant (P> 0.05); (5) Quality of life: There was no significant difference in the quality of life between the two groups before treatment (P> 0.05), while after treatment, the observation group was higher than the control group, the difference was statistically significant (P <0.05). Conclusion Treatment of coronary heart disease with anxiety and depression using psychological counseling combined with fluprofen tromethamine tablets can effectively alleviate patients with anxiety, depression, improve treatment compliance and CHD treatment, with a certain safety, it is conducive to improving the quality of life of patients.
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