维生素E联合行为疗法在慢性酒精中毒精神障碍患者治疗中的临床分析

Clinical analysis of vitamin E combined with behavior therapy in the treatment of patients with chronic alcoholism mental disorder

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2017, 44(5)
作者
作者单位

南充市中心医院急诊科 ;
南充市中心医院急诊科 ;

摘要
摘要:目的:探讨维生素E联合行为疗法在慢性酒精中毒精神障碍患者治疗中的临床疗效分析。方法:选取我院2014年1月至2016年1月期间收治的80例慢性酒精中毒致精神障碍的患者作为研究对象,按照随机数字表的方法分为观察组(n=40)和对照组(n=40),对照组患者采用维生素E进行治疗,观察组在对照组的基础上联合实施行为疗法进行干预。分别对两组患者治疗前后的精神症状与认知功能、复饮率生活质量进行比较,其中精神症状采用阴性和阳性症状量表(PANSS)评定,认知功能采用威斯康星卡片分类测验(WCST)进行评定,生活质量则采用(WHOQL-BREF)进行评定。结果:经比较,治疗前后,两组患者的随机错误数、持续错误数、正确次数、完成分类数、PANSS、总测验比较差异有统计学意义,其中观察组治疗后明显更优于对照组(P<0.05);同时,观察组患者治疗后的WHOQL-BREF量表评分亦明显高于对照组和治疗前(P<0.05), 且治疗后随访4周发现,观察组复饮率率为5(12.50%),对照组复饮率为27(67.50%),两组间差异有统计学意义(P<0.05)。结论:维生素E联合行为疗法可以改善慢性酒精中毒精神障碍患者对饮酒的拒绝程度,同时提高了患者的正确认知行为和生活质量,值得推广。
Abstract
Abstract: Objective: To investigate the clinical efficacy of vitamin E combined with behavior therapy in the treatment of patients with chronic alcoholism mental disorders. Methods: 80 chronic alcoholic patients in our hospital from January 2014 to January 2016 were selected from the poisoning caused by mental disorder patients as the research object, according to the random number table method divided into observation group (n=40) and control group (n=40), Patients in the control group were treated with vitamin E, and the observation group was treated with behavioral therapy on the basis of the control group. Respectively before and after treatment in two groups of patients with psychiatric symptoms and cognitive function, relapse rate to compare the quality of life, including psychiatric symptoms by the positive and Negative Syndrome Scale (PANSS) assessment of cognitive function, the Wisconsin Card Sorting Test (WCST) were assessed by the quality of life (WHOQL-BREF) assessment. Results: by comparison, before and after the treatment, the random error of the two groups of patients, the number of persistent error number, correct number, number of categories completed, PANSS test, the difference was statistically significant, the observation group after treatment were significantly better than the control group (P<0.05); at the same time, the observation group of patients after treatment, the scores of WHOQL-BREF was also higher than that of control group and before treatment (P<0.05), and followed up for 4 weeks after treatment, the observation group relapse rate was 5 (12.50%), the control group relapse rate was 27 (67.50%), the difference was statistically significant between the two groups (P<0.05). Conclusion: vitamin E combined with behavioral therapy can improve the refusal rate of alcohol consumption in patients with chronic alcoholism, and improve the correct cognitive behavior and quality of life of patients. It is worth popularizing.
关键词
关键词:维生素E;行为疗法;慢性酒精中毒;生活质量
KeyWord
Key words: vitamin E; behavior therapy; chronic alcoholism; quality of life
基金项目
页码 864-866
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张娴*,张应宏,杜平,黄洁. 维生素E联合行为疗法在慢性酒精中毒精神障碍患者治疗中的临床分析 [J]. 国际精神病学杂志. 2017; 44; (5). 864 - 866.

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