| Abstract |
【Abstract】Objective: To study the effect of sertraline in the treatment of stroke patients with anxiety, depressive disorder and cognitive function. METHODS: A total of 60 patients with cerebral stroke who were admitted to our hospital from February 2016 to February 2018 were randomly selected. The patients were divided into two groups according to the treatment method: the stroke unit routine treatment group (conventional treatment group, n=30) and Based on the routine treatment of stroke units based on the early sertraline treatment group (early treatment group, n=30), the HAMA score, HAMD score, NIHSS score, MMSE score, MoCA score, and BI score were statistically analyzed for the two groups of patients. Results; Compared with before treatment, the HAMA score, HAMD score, and NIHSS score were significantly lower in the two groups after treatment (P<0.05); the HAMA score and HAMD of the early treatment group were higher than those of the conventional treatment group after treatment. The scores and NIHSS scores were significantly lower (P<0.05), but there was no significant difference in the HAMA score, HAMD score, and NIHSS score between the two groups before treatment (P>0.05). Compared with before treatment, the MMSE score, MoCA score, and BI score were significantly higher in the two groups after treatment (P<0.05); the MMSE score, MoCA score, and the early treatment group were higher than those in the conventional treatment group after treatment. BI scores were significantly higher (P<0.05), but there was no significant difference in MMSE scores, MoCA scores, and BI scores between the two groups before treatment (P>0.05). Conclusion: Early sertraline treatment of stroke can effectively improve the patients anxiety, depression and cognitive function.
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