男性首发精神分裂症患者的流行病学调查及临床诊治探讨

Epidemiological investigation and clinical diagnosis and treatment of male first-episodeschizophrenia

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2019, 46(3)
作者
作者单位

河南省驻马店市第二人民医院 ;

摘要
[摘要] 探究男性首发精神分裂症患者的流行病学特点,为临床采取相关诊治措施提供参考依据。方法 采用分层多级随机抽样法选取3650名男性居民,以中文版复合性国际诊断问卷3.0(CIDI 3.0)作为筛查工具,国际疾病及相关健康问题分类第10版(ICD-10)作为诊断标准,统计男性首发精神分裂症发病率,并收集年龄、婚姻状况、吸烟史、家庭经济收入、阳性家族史、受教育程度、户籍性质等临床资料,分析男性首发精神分裂症相关影响因素及独立危险因素。结果 3650名男性居民中,92例确诊为首发精神分裂症,总患病率为2.52%(92/3650),其中时点患病率1.21%(44/3650),终生患病率1.32%(48/3650);不同婚姻状况、吸烟史、家庭经济收入、阳性家族史、受教育程度、户籍性质男性首发精神分裂症患病率相比,差异有统计学意义(P<0.05);经Logistic回归分析可知,单身(未婚、离异、丧偶)、存在阳性家族史、伴有吸烟史、家庭经济收入偏低、受教育程度低、农村户籍是男性首发精神分裂症的独立危险因素(P<0.05)。结论 男性首发精神分裂症发病率高,与单身(未婚、离异、丧偶)、存在阳性家族史、伴有吸烟史、家庭经济收入偏低、受教育程度低、农村户籍等因素密切相关,临床应根据上述危险因素采取针对性诊治措施,以便及早确诊,制定合理治疗方案,确保治疗效果,改善预后情况。
Abstract
[Abstract] Objective To investigate the epidemiological characteristics of male patients with first-episode schizophrenia, and provide reference for clinical diagnosis and treatment. Methods A stratified multi-level random sampling method was used to select 3650 male residents. The Chinese version of CIDI 3.0 was used as a screening tool. The 10th edition of the International Classification of Diseases and Related Health Problems (ICD-10) was used as a diagnostic criterion. The incidence of male first-episode schizophrenia was counted. Age, marital status and smoking were collected. Clinical data such as smoking history, family income, positive family history, education level and the nature of household registration were used to analyze the related factors and independent risk factors of male first-episode schizophrenia.ResultsAmong 3 650 male residents, 92 were diagnosed as first-episode schizophrenia, with a total prevalence rate of 2.52% (92/3650), including 1.21% (44/3650) at the time point and 1.32% (48/3650) at the lifetime. Men with different marital status, smoking history, family income, positive family history, educational level and household registration were first-episode psychosis. The prevalence of schizophrenia was significantly different (P < 0.05). Logistic regression analysis showed that single (unmarried, divorced, widowed), positive family history, smoking history, low family income, low education level and rural household registration were independent risk factors for male first-episode schizophrenia (P < 0.05).Conclusion The incidence of male first-episode schizophrenia is high, which is closely related to single (unmarried, divorced, widowed), positive family history, smoking history, low family income, low education level, rural household registration and other factors. We should formulate a reasonable treatment plan to ensure the treatment effect and improve the prognosis.
基金项目
页码 445-447
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赵玉香*. 男性首发精神分裂症患者的流行病学调查及临床诊治探讨 [J]. 国际精神病学杂志. 2019; 46; (3). 445 - 447.

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