| Abstract |
Objective: To explore the correlation between risk factors of cerebral microhemorrhage and cognitive impairment. Methods: 60 cases of patients with stroke in our hospital from May 2018 to May 2019 were randomly selected and divided into two groups: one group with cerebral microhemorrhage (30 cases) and the other group without cerebral microhemorrhage (30 cases). The general data, clinical biochemical indicators and cognitive functions of the two groups were statistically analyzed. The risk factors of cerebral microhemorrhage were analyzed by multiple logistic regression. The correlations between cognitive impairment and cognitive impairment were analyzed. Results: The proportions of male, hypertension and stroke of the with cerebral microhemorrhage group were significantly higher (P < 0.05). The age, NIHSS score, serum IL-6 and hs-CRP levels were significantly higher than the without cerebral microhemorrhage (P < 0.05). Multivariate logistic regression analysis showed that the risk factors of cerebral microhemorrhage included age, hypertension, stroke, IL-6, hs-CRP, ApoE, Aβ and MMP-9 (P < 0.05). Age, hypertension, stroke, IL-6, hs-CRP, ApoE, Aβ, MMP-9 and MMSE scores, MoCA scores were negatively correlated (P < 0.05). Conclusion: The risk factors of cerebral microhemorrhage are significantly correlated with cognitive impairment.
|