| Abstract |
Objective To explore the correlation between sleep and oxygen monitoring and the level of negative psychological and cognitive impairment in COPD patients. Methods 123 COPD patients treated in our hospital from April 2017 to April 2019 were divided into group A (mild, n=34), group B (moderate, n=39), group C (severe, n=35), and group D (extremely severe, n=15) according to FEV1/FVC and FEV1 percentage of predicted value. Sleep monitoring indicators, Anxiety (SAS), Depression (SDS) and Cognitive Function (MMSE and MoCA) of four groups were compared. Spearman correlation analysis was used to analyze the correlation between sleep monitoring indicators and patients psychological and cognitive functions. Results I+II, AHI, MAI and TS90% in group D were significantly higher than those in group A, B and C, REM, LSaO2 and MSAO2 were significantly lower than those in group A, B and C(P<0.05). The SAS and SDS scores in group D were significantly higher than those in group A, B and C, MMSE and MoCA scores were significantly lower than those in group A, B and C(P<0.05), There were significant differences in the above indexes between the four groups(P<0.05). Negative psychological level was positively correlated with shallow sleep time, AHI, MAI and TS90%, and negatively correlated with REM(P<0.05), Cognitive dysfunction was negatively correlated with shallow sleep time, AHI, MAI and TS90%, and positively correlated with REM(P<0.05). Conclusion COPD patients have a certain decline in sleep quality, and their sleep and blood oxygen indicators are strongly correlated with the level of negative psychological and cognitive impairment.
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