中频电辅助治疗对老年抑郁症躯体疼痛症状和生活质量的影响

Auxiliary Effect of Medium Frequency Electrotherapy on Concomitant Pain and Quality of Life for Geriatric Depression

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2019, 46(6)
作者
作者单位

无锡市精神卫生中心 ;
苏州市广济医院 ;

摘要
目的:探索中频电治疗联合SSRIs类抗抑郁药对老年抑郁症伴躯体疼痛患者抑郁症状、疼痛症状和生活质量的影响。方法:将61名老年抑郁症患者随机分成研究组和对照组。研究组给予中频电治疗联合SSRIs类抗抑郁药物,对照组给予中频电治疗假刺激联合SSRIs类抗抑郁药物,在基线期、1周末、2周末、4周末,采用汉密尔顿抑郁量表(HAMD)、简式McGill疼痛问卷来评估患者的临床症状。4周末采用生活质量量表、副反应量表评估生活质量状况和药物副反应情况。结果:两组在治疗的第1、2、4周末HAMD得分、疼痛症状得分均比基线期明显减少,通过重复测量方差对比,时间效应,交叉效应显著,在第2、4周末研究组HAMD分值,疼痛分值明显小于对照组,差异均具有显著性(P<0.05)。在第4周末汉密尔顿抑郁量表评分均值显著小于对照组,差异具有显著性(P<0.05)。研究组患者在生活质量躯体健康方面的生理机能、生理职能、躯体疼痛维度评分在治疗4周末显著大于对照组(P<0.05)。结论:1.中频电治疗对老年抑郁症伴躯体疼痛患者的抑郁症状、躯体疼痛症状具有明显的增效作用,可显著提高老年抑郁症患者生活质量。
Abstract
Objective: To explore the effect of medium frequency electrotherapy (MFET) on depressive symptoms, pain symptoms and quality of life in Geriatric Depression patients with concomitant pain (GDCP). Methods: A total of 61 GDCP were recruited from Wuxi mental health center and randomly divided into the treatment group and control group. Treatment group was given MFET and SSRIs therapy. Control group was given SSRIs therapy and sham stimulation regimen. Hamilton depression rating scale and McGill Pain Questionnaire were used to evaluate the severity of depression and pain, at the baseline,1-weekend, 2- weekend and 4-weekend of treatment respectively. Short Form 36 Health Survey Questionnaire and Treatment Emergent Symptom Scale were employed at the baseline and 4-week follow-up. Result:The change of HAMA index,visual analogous scale (VAS), present pain intensity (PPI), pain rating index (PRI) before and after treatment were all statistically significant. The P value of time effect and the interaction effect are both <0.05, by re-testing the variance test. The change of HAMD index in treatment group was greater than control group at 2-weekend and 4-weekend. The index of HAMD, VAS, PPI, and PRI of treatment group was lesser than control group at the end of 4 weeks. The scores of treatment group were significantly higher than those of the control group after 4 weeks of treatment in terms of physiological function, physiological function and somatic pain dimension (P<0.05). Conclusion: As an adjuvant therapy, MFET show significantly auxiliary effect, and improve the quality of life of GDCP.
关键词
老年抑郁症;中频电治疗;疼痛症状;生活质量
KeyWord
geriatric depression; medium frequency electrotherapy; concomitant pain; quality of life.
基金项目
页码 1016-1019
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王栋*,朱华,吴维冬,王秀艳. 中频电辅助治疗对老年抑郁症躯体疼痛症状和生活质量的影响 [J]. 国际精神病学杂志. 2019; 46; (6). 1016 - 1019.

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