芬吗通联合坤泰胶囊治疗更年期抑郁的临床疗效及对睡眠质量的影响

Clinical efficacy of femoston combined with Kuntai capsule in treating menopausal depression and its effect on sleep quality

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2019, 46(6)
作者
作者单位

江西省宜春市铜鼓县人民医院 ;

摘要
目的:探讨芬吗通联合坤泰胶囊治疗更年期抑郁的临床疗效及对睡眠质量的影响。方法:以2018年5月-2019年5月本院收治的58例更年期抑郁患者为对象,按电脑数字表法随机分作两组,每组各29例,对照组予以芬吗通治疗,试验组展开芬吗通联合坤泰胶囊治疗,对比两组疗效及睡眠质量改善情况。结果:治疗后,试验组促卵泡激素是(53.61±2.17)U/L,较对照组的(62.51±2.25)U/L低,雌二醇是(68.32±2.13)pmol/L,较对照组的(60.24±2.25)pmol/L高,差异有统计学意义(P<0.05);治疗后,试验组更年期妇女症状评分表、汉密尔顿抑郁量表评分均较对照组低,差异有统计学意义(P<0.05);治疗后,试验组匹兹堡睡眠质量指数量表中的睡眠质量、睡眠时间、睡眠障碍评分均较对照组低,差异有统计学意义(P<0.05)。结论:更年期抑郁通过芬吗通联合坤泰胶囊治疗可有效改善性激素水平、更年期及抑郁症状,进而提升其睡眠质量。
Abstract
Objective: To investigate the clinical efficacy of femoston combined with Kuntai Capsule in the treatment of menopausal depression and its impact on sleep quality.Methods: 58 cases of menopausal depression patients admitted to our hospital from May 2018 to May 2019,According to the computer digital table method randomly divided into two groups , each group of 29 cases,The control group was treated with femoston, and the experimental group was treated with femoston and Kuntai capsules. The efficacy and sleep quality improvement of the two groups were compared.Results: After treatment, the follicle stimulating hormone in the experimental group was (53.61±2.17) U/L, which was lower than that of the control group (62.51±2.25) U/L, and estradiol was (68.32±2.13) pmol/L, compared with the control group. (60.24±2.25) pmol/L high, with statistically significant (P<0.05).After treatment, the kupperman index, hamilton depression scale are lower than the control group,with statistically significant (P<0.05).After treatment, the sleep quality, sleep time and sleep disorder scores in the Pizids sleep quality index table were lower than those in the control group, with statistically significant (P<0.05).Conclusion: Menopausal depression can effectively improve sex hormone levels, menopause and depressive symptoms through the combination of femoston and Kuntai Capsules, thus improving their sleep quality.
关键词
芬吗通;坤泰胶囊;更年期抑郁;治疗;睡眠质量
KeyWord
Femoston; Kuntai capsule; Menopausal depression; Treatment; Sleep quality
基金项目
页码 1073-1076
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杨文英*. 芬吗通联合坤泰胶囊治疗更年期抑郁的临床疗效及对睡眠质量的影响 [J]. 国际精神病学杂志. 2019; 46; (6). 1073 - 1076.

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