Journal of International Psychiatry

Objective To investigate the main impact factors of the stability of patients with schizophrenia in Hunan Province. Methods With the fund of National Central Subsidy for Local Management and Treatment of Severe Mental Illness (known as "686" project), the data in the information system was recorded from Nov. 2010 to June 2018 in Hunan Province. A total of 144,159 patients with schizophrenia were enrolled after clearing the data. The Chi-Square Test was used to infer the relationship between the stability of the disease and the factors in research. The regression analysis showed the quantitative correlation between disease stability and significant factors. Results The lack of insight and irregular medication brings the most significant risks to the disease instability, and their Orient Ratio are 3.42 and 2.21 respectively. Some factors, such as age below 41 years old, farmer, poor, having family history or gender of male, are more positively correlated with the instability. Conclusion Improving self-knowledge, supervising regular medication, and disease tracking of the specific age and the low income are crucial for improving the stability of patients with schizophrenia.

Schizophrenia；Stability of schizophrenia；Risk factor