Journal of International Psychiatry

Objective: To explore the clinical value of sertraline combined with dredging therapy in the treatment of depression with impaired glucose tolerance. Methods: 104 patients with depression and impaired glucose tolerance admitted to our hospital from February 2017 to July 2018 were selected as the study objects. They were divided into two groups according to the digital random method. The control group was treated with a single sertraline, while the observation group was treated with the combination of dredging therapy on the basis of this, and the treatment effect of the two groups was compared. Results: before treatment, there was no difference in blood glucose level between the two groups (P > 0.05); after treatment, the level of 2hPG in the observation group was lower than that in the control group (P < 0.05); compared with the control group, the treatment efficiency of the observation group was higher, and the difference between the groups was significant (P < 0.05); before treatment, the scores of the two groups were not comparable (P > 0.05); after treatment, compared with the control group, the HAMD and SDS scores of the observation group were all higher The quality of life score of the observation group was higher than that of the control group (P < 0.05), but there was no difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion: sertraline and dredging therapy are effective in the treatment of depression with abnormal glucose tolerance.

depression, sertraline, dredging therapy, abnormal glucose tolerance