Journal of International Psychiatry

Objective: To study and analyze the characteristics of mood disorders in patients with glioma before and after operation. Methods: from December 2017 to December 2019, 100 patients with gliomas underwent neurosurgery in our hospital, as the observation subjects in this study. Hamilton Anxiety Rating Scale (HAMA) and Hamilton Depression Rating Scale (HAMD) were used to evaluate the mood characteristics of patients one day before and seven days after operation. By means of multiple linear regression analysis, the influencing factors of HAMD score in patients with glioma were studied. Results: on the 7th day after operation, the HAMD score was significantly lower than that before operation (P < 0.05), and the incidence of postoperative depression was significantly lower than that before operation (P < 0.05). There was no significant difference in HAMA score and anxiety rate before and after operation (P > 0.05). According to the different tumor location, pathological grade and tumor side of gliomas, the HAMD scores of patients with frontotemporal lobe tumors, high-grade pathological patients and right tumors after operation were lower than those before operation (P < 0.05). Through multiple linear regression analysis, the key factor affecting the preoperative HAMD score of patients is the family economic income, and the higher the family economic income, the lower the preoperative HAMD score of patients, the negative correlation between them. Conclusion: most of the patients with glioma before and after neurosurgery have mood disorders of different degrees. The severity of depression may be related to the tumor growth location. Family income seriously affects the preoperative HAMD score of patients with glioma.

glioma; Neurosurgery; preoperative and postoperative; mood disorders; characteristic analysis; depression