糖尿病前期与缺血性卒中患者卒中后抑郁的相关性研究

A study on the relationship between pre diabetes and post-stroke depression in patients with ischemic stroke

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2021, 48(1)
作者
作者单位

河南省南阳市卧龙区第一人民医院 ;

摘要
目的:探讨分析糖尿病前期与缺血性卒中患者的卒中后抑郁(PSD)发病率以及发病程度相关性。方法:选取本院2016年1月至2019年6月间收治200例急性缺血性卒中患者,依据患者血糖水平分为正常血糖组(n=80)与糖尿病前期组(n=120),糖尿病前期组依据自愿接受干预控制原则分为血糖控制亚组(n=68)、无血糖控制亚组(n=52)。分别于患者入院时、卒中后2w、卒中后3个月以及卒中后6个月诊断并评估患者抑郁程度,对比分析正常血糖组与糖尿病前期组(血糖控制亚组、无血糖控制亚组)患者PSD患病率以及卒中后6个月各组患者抑郁程度情况。结果:正常血糖组与糖尿病前期组患者入院时、卒中后2w的PSD发生率对比无明显差异(P>0.05);卒中后3个月以及卒中后6个月糖尿病前期组患者PSD发生率相比正常血糖组明显更高(P<0.05);卒中后3个月以及卒中后6个月血糖控制亚组患者PSD发生率相比无血糖控制亚组明显更高(P<0.05);卒中后6个月糖尿病前期组患者PSD病情程度相比正常血糖组明显更高(P<0.05);卒中后6个月无血糖控制亚组患者PSD病情程度相比血糖控制亚组明显更高(P<0.05);卒中后6个月血糖控制亚组患者PSD病情程度相比正常血糖组无明显差异(P>0.05)。结论:缺血性卒中合并糖尿病前期患者更易卒中后抑郁症,监测缺血性卒中血糖水平并进行血糖控制对于降低卒中后抑郁症发生具有重要作用。
Abstract
Objective: To explore the correlation between the incidence and degree of post-stroke depression (PSD) in pre diabetes and ischemic stroke patients. Methods: from January 2016 to June 2019, 200 patients with acute ischemic stroke were divided into normal blood glucose group (n = 80) and pre diabetes group (n = 120) according to their blood glucose level. Pre diabetes group was divided into blood glucose control group (n = 68) and non blood glucose control group (n = 52) according to the principle of voluntary intervention and control. At the time of admission, 2 weeks, 3 months and 6 months after stroke, the depression degree of the patients was diagnosed and evaluated. The prevalence of PSD and the depression degree of the patients in the normal blood glucose group and the pre diabetes group (blood glucose control group, non blood glucose control group) were compared and analyzed. Results: there was no significant difference in the incidence of PSD between the normal blood glucose group and the pre diabetes group at the time of admission and 2 weeks after stroke (P > 0.05); the incidence of PSD in the pre diabetes group at 3 and 6 months after stroke was significantly higher than that in the normal blood glucose group (P < 0.05); the incidence of PSD in the blood glucose control group at 3 and 6 months after stroke was significantly higher than that in the non blood glucose control group The level of PSD in the pre diabetes group was significantly higher than that in the normal blood glucose group (P < 0.05); the level of PSD in the non blood glucose control group was significantly higher than that in the blood glucose control group (P < 0.05); the level of PSD in the blood glucose control group was no significant difference compared with the normal blood glucose group (P > 0.05). Conclusion: Patients with ischemic stroke and prediabetes are more likely to suffer from post-stroke depression. It is important to monitor the blood glucose level of ischemic stroke and control the blood glucose level in order to reduce the incidence of post-stroke depression.
关键词
糖尿病前期;缺血性卒中;卒中后抑郁症;影响作用
KeyWord
prediabetes; ischemic stroke; post-stroke depression; effect
基金项目
页码 88-91
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院晓英*. 糖尿病前期与缺血性卒中患者卒中后抑郁的相关性研究 [J]. 国际精神病学杂志. 2021; 48; (1). 88 - 91.

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