重复经颅磁刺激对卒中后认知功能障碍患者认知及情绪的影响
Effect of Repeated Transcranial Magnetic Stimulation on Cognition and Emotion in Patients with Cognitive Impairment after Apoplexy
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(3) |
| 作者 |
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| 作者单位 |
郑州大学第五附属医院 ;
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| 摘要 |
研究重复经颅磁刺激对卒中后认知功能障碍患者认知及情绪的影响。方法 选择2017年1月到2019年11月100例卒中后认知功能障碍患者作为研究对象，使用数字随机表法均分为两组，对照组给予常规治疗，观察组在此基础上采用重复经颅磁刺激治疗。比较两组的蒙特利尔认知功能评估量表(MoCA)、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、相关事件电位(ERP)。结果 对照组治疗后的MoCA显著低于研究组，HAMD、HAMA显著高于研究组，差异均有统计学意义(P<0.01)。两组治疗后的N1潜伏期、P2潜伏期比较，差异均无统计学意义(P>0.05)；对照组治疗后的N2潜伏期、P3潜伏期显著高于研究组，P3波幅显著低于研究组，差异均有统计学意义(P<0.001)。结论 卒中后认知功能障碍患者采取重复经颅磁刺激可显著改善认知功能，降低抑郁、焦虑情绪。
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| Abstract |
Objective To study the effect of repeated transcranial magnetic stimulation on cognition and emotion in patients with cognitive impairment after apoplexy. Methods A total of 100 patients with post-stroke cognitive impairment from January 2017 to November 2019 were selected as the objects. The patients were divided into the two groups using the digital random table method. The control group was given conventional treatment, and the observation group was repetitively transcranial and magnetic stimulation treatment. The Montreal cognitive function assessment scale (MoCA), Hamilton depression scale (HAMD), Hamilton anxiety scale (HAMA), and related event potential (ERP) were compared between the two groups. Results The MoCA in the control group after treatment was significantly lower than that in the study group, and HAMD and HAMA were significantly higher than those in the study group. The differences were statistically significant (P<0.01). There was no significant difference in the N1 latency and P2 latency between the two groups after treatment (P>0.05); the N2 latency and P3 latency after treatment in the control group were significantly higher than those in the study group, and the P3 amplitude was significantly lower than in the study group. There was statistical significance (P<0.001). Conclusion Repetitive transcranial magnetic stimulation in patients with cognitive impairment after stroke can significantly improve cognitive function and reduce depression and anxiety.
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| 关键词 |
重复经颅磁刺激；卒中；认知功能；抑郁；焦虑；ERP
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| KeyWord |
Repetitive Transcranial Magnetic Stimulation; Stroke; Cognitive Function; Depression; Anxiety; ERP
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| 基金项目 |
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| 页码 |
523-526 |
赵静*.
重复经颅磁刺激对卒中后认知功能障碍患者认知及情绪的影响 [J].
国际精神病学杂志.
2020; 47; (3).
523 - 526.