Journal of International Psychiatry

[Abstract] Objective To analyze the unhealthy mental state and pain changes of patients with lumbar disc herniation undergoing minimally invasive surgery after fluoxetine treatment. Methods 111 patients with lumbar disc herniation in our hospital were grouped by random number table. Both groups of patients underwent percutaneous intervertebral foramenectomy. On this basis, 55 patients in the control group were given routine psychological intervention before operation, and 56 patients in the observation group Fluoxetine oral therapy was added to the control group to compare the changes in anxiety, depression, postoperative pain, and quality of life of the two groups of patients before and after intervention. Results After treatment, the SAS and SDS scores of the observation group were lower than those of the control group, the SF-36 score was higher than the control group, and the VAS scores were lower than those of the control group 1, 3, and 7 days after surgery (P<0.05). Conclusion Fluoxetine can effectively eliminate the negative emotions of patients with lumbar disc herniation during perioperative period, reduce postoperative pain, and improve the quality of life.