单次亚麻醉剂量氯胺酮对乳腺癌根治患者术后早期情绪及恢复质量的影响

Effects of single sub-narcotic dose of ketamine on early postoperative mood and recovery quality of patients undergoing radical mastectomy

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2021, 48(1)
作者
作者单位

郑州大学第一附属医院 ;

摘要
【摘要】探讨乳腺癌根治患者采用单次亚麻醉剂量氯胺酮对术后早期情绪及恢复质量的影响。方法 纳入2018年9月~2019年9月期间我院接诊的120例乳腺癌患者作为本次研究对象,掷币法将其分为两组,两组患者均拟行乳腺癌根治术,均在同样的麻醉方法下进行手术,对照组60例患者术后镇痛予以单纯静脉镇痛泵,观察组60例患者术后镇痛予以单次亚麻醉剂量氯胺酮+静脉镇痛泵,比较两组患者焦虑、抑郁情绪评分、疼痛评分及恢复质量评分。结果 术后第3,观察组患者SAS评分及SDS评分均明显降低,且低于对照组,焦虑、抑郁情绪病例数少于对照组,差异明显(P<0.05);观察组身体舒适度、情绪状态、心理支持及疼痛评分及总分均高于对照组,差异显著(P<0.05)。结论 单次亚麻醉剂量氯胺酮能快速改善围术期乳腺癌患者早期焦虑、抑郁状态,提高乳腺癌患者术后恢复质量,利于患者术后康复,值得推荐。
Abstract
【Abstract】Objective To explore the effect of single sub-anaesthetic dose of ketamine on early postoperative mood and recovery quality in patients with radical breast cancer. Methods A total of 120 breast cancer patients admitted to our hospital from September 2018 to September 2019 were included in this study. The coin toss method was divided into two groups. Both groups of patients were planned to undergo radical breast cancer surgery. The operation was performed under the same anesthesia method. 60 patients in the control group were given a simple intravenous analgesia pump for postoperative analgesia, and 60 patients in the observation group were given a single sub-narcotic dose of ketamine + intravenous analgesia for postoperative analgesia. Patient anxiety, depression score, pain score and recovery quality score. Results In the third postoperative period, the SAS score and SDS score of the observation group were significantly lower than those of the control group. The number of anxiety and depression cases was less than the control group, the difference was significant (P<0.05); the body comfort and emotion of the observation group The state, psychological support, pain score and total score were higher than those in the control group, the difference was significant (P<0.05). Conclusion A single sub-anaesthetic dose of ketamine can quickly improve the early anxiety and depression of perioperative breast cancer patients, improve the quality of postoperative recovery of breast cancer patients, and benefit the postoperative recovery of patients. It is worth recommending.
基金项目
页码 122-124
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杨爱民*. 单次亚麻醉剂量氯胺酮对乳腺癌根治患者术后早期情绪及恢复质量的影响 [J]. 国际精神病学杂志. 2021; 48; (1). 122 - 124.

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