合并抑郁症对PCI术后支架内再狭窄的影响

Effect of Combined Depression on Restenosis in Stent After PCI

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2020, 47(6)
作者
作者单位

河南科技大学第一附属医院 ;

摘要
【摘要】 研究合并抑郁症对经皮冠状动脉介入治疗(PCI)术后支架内再狭窄的影响。方法 选择本院2017年5月到2020年5月92例行PCI患者作为研究对象,根据是否合并抑郁症分为抑郁组46例和无抑郁组46例。比较两组的汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、匹兹堡睡眠质量指数(PSQI)、生活质量量表(WHOQOL-BREF)、临床疗效、PCI术后支架内再狭窄率。结果 抑郁组的HAMD、HAMA、PSQI评分显著高于无抑郁组,WHOQOL-BREF评分显著低于无抑郁组,差异均有统计学意义(P<0.05)。抑郁组的总有效率80.43%显著低于无抑郁组的总有效率95.65%,差异有统计学意义(P<0.05)。抑郁组PCI术后支架内再狭窄率21.74%显著高于无抑郁组PCI术后支架内再狭窄率6.52%,差异有统计学意义(P<0.05)。结论 合并抑郁症会直接导致患者PCI术后睡眠及生活质量、临床疗效下降,支架内再狭窄率升高。
Abstract
[Abstract] Objective To study the effect of combined depression on restenosis in stent after percutaneous coronary intervention (PCI). Methods Ninety-two patients with PCI in our hospital from May 2017 to May 2020 were selected as the research object. According to whether they were combined with depression, they were divided into 46 cases in the depression group and 46 cases in the non-depression group. Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), Pittsburgh Sleep Quality Index (PSQI), Quality of Life Scale (WHOQOL-BREF), clinical efficacy, in-stent restenosis rate after PCI were compared between the two groups. Results The HAMD, HAMA, and PSQI scores of the depression group were significantly higher than those of the non-depression group, and the WHOQOL-BREF score was significantly lower than that of the non-depression group, and the differences were statistically significant (P<0.05). The total effective rate in the depression group was 80.43%, which was significantly lower than that in the non-depression group, 95.65%, the difference was statistically significant (P<0.05). The post-PCI stent restenosis rate in the depression group was 21.74%, which was significantly higher than the non-depression group PCI stent restenosis rate, 6.52%, the difference was statistically significant (P<0.05). Conclusion Complicated depression will directly lead to a decrease in sleep, quality of life and clinical efficacy after PCI, and an increase in the rate of in-stent restenosis.
关键词
【关键词】抑郁症;PCI;睡眠质量;生活质量;支架内再狭窄
KeyWord
Key words Depression; PCI; Sleep Quality; Quality of Life; In-Stent Restenosis
基金项目
页码 1204-1206
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程建新*. 合并抑郁症对PCI术后支架内再狭窄的影响 [J]. 国际精神病学杂志. 2020; 47; (6). 1204 - 1206.

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