International Journal of Clinical Research

Objective To explore the value of amlodipine besylate combined with irbesartan in the treatment of elderly hypertension. Methods A total of 28 elderly hypertensive patients (from April 2023 to April 2024) were diagnosed in our hospital and randomly divided into 2 groups with 14 cases in each group. The control group was given oral irbesartan only, and the observation group was given oral irbesartan combined with amlodipine besylate. The treatment of the 2 groups was evaluated according to blood pressure index, therapeutic effect evaluation and adverse reactions. Results The systolic blood pressure and diastolic blood pressure were lower in the observation group than in the control group after intervention (P < 0.05). The clinical effect evaluation showed that the total effective rate of the observation group was significantly improved compared with the control group (P < 0.05). There was no statistical significance in the total incidence of adverse reactions between the two groups (P > 0.05). Conclusion The combined application of amlodipine besylate and irbesartan in the treatment of elderly hypertension has a significant improvement in the effect of blood pressure control, and has a good safety guarantee.

Elderly hypertension; Amlodipine besylate; Irbesartan