International Journal of Clinical Research

Objective To explore the practical effectiveness of combining negative pressure drainage technology with expanded skin grafting technology in the treatment of large area burn infections and difficult to heal wounds. Methods Sixty patients with large area burn infections and difficult to heal wounds admitted to our hospital from October 2023 to October 2024 were selected as the study sample. They were randomly divided into a reference group and an experimental group, with 30 cases in each group. The reference group was treated with expanded skin grafting technology, while the experimental group was treated with negative pressure drainage technology combined with expanded skin grafting technology. Compare the differences in clinical efficacy between two groups. Results The NRS score during dressing change in the experimental group was significantly lower (P<0.05), and the wound healing time was significantly shorter (P<0.05); The incidence of adverse reactions in the experimental group was significantly lower (P<0.05). Conclusion The combination of negative pressure drainage technology and expanded skin grafting technology can alleviate patient pain, promote wound healing, and reduce the incidence of adverse reactions in the treatment of large area burn infections with difficult to heal wounds.

Large area burns; Difficult to heal wounds caused by infection; Negative pressure drainage technology; Expansion and skin grafting technology; Efficacy analysis