Journal of International Psychiatry

【Abstract】Objective: To observe the effect of group puzzle games combined with piracetam on the cognitive function, quality of life and mental state of patients with cognitive impairment in young and old. Methods: A total of 121 elderly and young patients with cognitive impairment admitted to our department between July 2017 and November 2019 were selected as the observation objects, and they were divided into a control group of 60 cases and an observation group of 61 cases. The control group was given piracetam And conventional nursing intervention, the observation group was given group puzzle games on the basis of the control group. After 6 months, the cognitive function, quality of life and psychological state of the two groups were compared. Results: The MMSE score and MoCA score of the two groups of patients were significantly improved after treatment (P<0.05). After treatment, the MMSE score and MoCA score of the observation group were significantly better than those of the control group (P<0.05). The QOL-AD score and ADL score of the two groups of patients increased significantly after treatment (P<0.05). After treatment, the QOL-AD score and ADL score of the observation group were significantly better than those of the control group (P<0.05). The SAS score and SDS score of the two groups of patients after treatment were significantly lower than those before treatment (P<0.05). After treatment, the SAS score and SDS score of the observation group were significantly lower than those of the control group (P<0.05). Conclusion: Group puzzle games combined with piracetam can effectively improve the cognitive function of patients with cognitive impairment in the elderly and young, improve the ability of daily living and improve the quality of life, thereby effectively reducing depression and anxiety.

[Keywords] group puzzle games; piracetam; cognitive impairment in the old and young; cognitive function; mental state