International Journal of Clinical Research

Background and objective: Biliary obstruction is a common clinical disease, and MRCP and ERCP play an important role in the diagnosis and treatment of biliary obstruction. study explores the localization, qualitative diagnosis, and treatment effects of MRCP and ERCP on biliary obstruction diseases. Methods Retrospective analysis of patients diagnosed with biliary obstruction who underwent MRCP examination and ERCP treatment from October 2022 to October2024. The patients were divided into jaundice group and non-jaundice group according to their clinical characteristics. The clinical characteristics, treatment, and accuracy of localization and qualitative diagnosis of the two groups were analyzed. Results A total of 78 patients with biliary obstruction who underwent MRCP examination and ERCP treatment were collected, with 39 cases in jaundice group and 39 cases in the non-jaundice group. The total bilirubin level and ALT level in the jaundice group were significantly lower than those before surgery, with significant differences, while total bilirubin and ALT levels in the non-jaundice group did not change significantly after surgery, with no significant differences. In this study, there were 58 cases of common bile duct stones, 3 cases of pancreatic cancer, 2 cases of cholangarcinoma, 2 cases of hepatocellular carcinoma, 7 cases of inflammatory stricture of the bile duct, 3 cases of inflammatory stricture the papilla, and 3 cases of ampullary tumors. In terms of localization diagnosis, in the jaundice group, the accuracy rate of localization diagnosis by MRCP was 87.18 by ERCP was 94.87%, and by the combination of both methods (MRCP ERCP) was 97.44 In the non-jaundice group, the accuracy rate of localization diagnosis by MRCP was 82.05%, by ERCP was 8.74%, and by the combination of both methods (MRCP ERCP) was 94.87%.In terms of qualitative diagnosis, in the jaundice group, the accuracy rate of qualitative diagnosis of MRCP was 82.0%, that of ERCP was 87.18%, and that of the combination of the two methods (MRCP ERCP) was 9231%. In the non-jaundice group, the accuracy rate of qualitative diagnosis of MRCP was 82.05%, that of ER was 87.18%, and that of the combination of the two methods (MRCP ERCP) was 92.31%. indicates that the combination of MRCP and ERCP has a high accuracy rate for the localization and qualitative diagnosis of biliary obstruction. Conclusion In the diagnosis of biliary obstruction diseases, MRCP and ERCP have their own advantages and disadvantages. By combining the strengths of both, accuracy of localization and qualitative diagnosis of biliary obstruction can be improved to some extent. In terms of treatment, the bilirubin and ALT levels in theundice group improved significantly after ERCP, indicating that ERCP is more effective in patients with biliary obstruction complicated with jaundice.

Magnetic resonance cholangiopancreatography(MRCP); Endoscopic retrograde cholangiopancreato-graphy(ERCP); Localization diagnosis; Qualitative diagnosis; Biliary obstruction