International Journal of Clinical Research

Objective To investigate the clinical therapeutic effect of clarithromycin combined with triple therapy on Helicobacter pylori infection related gastritis. Methods 80 patients with Helicobacter pylori infection related gastritis admitted to our hospital from February 2024 to February 2025 were selected as the study sample. They were randomly divided into a reference group (triple therapy) and an experimental group (clarithromycin combined triple therapy) using envelope randomization, with 40 patients in each group. Compare the differences in effectiveness between the two groups. Results In terms of symptom scores, there was no significant difference between the two groups before treatment (P>0.05). After treatment, the experimental group had significantly lower scores for acid reflux, belching, and upper abdominal pain (P<0.05); In terms of treatment effectiveness, the experimental group was significantly higher (P<0.05). Conclusion The combination therapy of clarithromycin and triple therapy has excellent therapeutic effects in the treatment of Helicobacter pylori infection related gastritis, effectively improving patient symptoms and enhancing treatment efficacy.

Clarithromycin; Triple therapy; Helicobacter pylori infection; Gastritis; Clinical efficacy