International Journal of Clinical Research

Objective To explore the expression characteristics and correlation of glycosylated hemoglobin (HbAlc) and hemoglobin (Hb) in patients with type 2 diabetes mellitus (T2DM) at high altitude. Methods 119 patients with T2DM from the Department of Endocrinology, Peoples Hospital of Hainan Prefecture, Qinghai Province (at an altitude of 3000m), 116 patients from the Department of Endocrinology, Third Peoples Hospital of Xining City (at an altitude of 2200m) and 200 patients from the Institute of Diabetes in the Affiliated Hospital of Fudan University in Shanghai (at an altitude of 2.19m) were selected as diabetes group and 15 non-diabetic patients as control group. Results T2DM at high altitude shows the high. Conclusion The serum Hb, HbAlc and other five indexes in the diabetic group were higher than those in the normal group, while albumin, neutrophils and lymphocytes were lower than those in the normal group (P<0.05). expression characteristics of HbAlc and Hb, and there is a close positive correlation between them, which indicates that Hb may have some influence on HbAlc of T2DM patients at high altitude, which can be comprehensively judged by combining multiple indexes.

High altitude area; Type 2 diabetes; Glycosylated hemoglobin; Hemoglobin