International Journal of Clinical Research

Objective To investigate the efficacy of Xin Huo Su combined with Red Flower Oral Liquid in treating 50 patients with refractory heart failure admitted to our hospital from January 2024 to December 2024. The patients were randomly divided into a control group and an observation group, each consisting of 25 patients. The control group received conventional anti-heart failure treatment, while the observation group received Xin Huo Su and Red Flower Oral Liquid in addition to conventional treatment. The study compared the heart function indicators (left ventricular ejection fraction, left ventricular end-diastolic diameter), 6-minute walk distance, BNP levels, and clinical outcomes before and after treatment. Results After treatment, the left ventricular ejection fraction of the observation group increased to (48.2±5.1)% compared to the control groups (42.3±4.8)%; the left ventricular end-diastolic diameter decreased to (55.6±4.3)mm compared to the control groups (59.8±4.7)mm; the 6-minute walk distance was greater than that of the control group; BNP levels decreased to (1256.3±215.4)pg/mL compared to the control groups (1789.5±246.7)pg/mL, with all differences being statistically significant (P<0.05). The overall effective rate of the observation group reached 88.0% (22/25), significantly higher than the control groups 68.0% (17/25) (P<0.05). Conclusion Xin Huo Su combined with Red Flower Oral Liquid is effective in treating refractory heart failure, improving heart function, enhancing exercise endurance, and reducing neuroendocrine factor levels, with significant clinical outcomes, making it worthy of promotion.

Xinhuo; Rhododendron oral liquid; Refractory heart failure; Clinical effect