International Journal of Clinical Research

This paper systematically reviews the research progress on the pathological mechanism of acupuncture and moxibustion intervention in tumor related complications in the past decade. Through sorting out 40 clinical studies, from the molecular mechanism level of neuroendocrine immune network regulation, inflammatory factor balance, oxidative stress regulation, combined with clinical application dimensions such as perioperative gastrointestinal function maintenance, radiation and chemotherapy toxicity control, cancerous pain management, depression improvement, etc., the multi target and multi-channel intervention characteristics of acupuncture and moxibustion are revealed. The existing evidence shows that acupuncture and moxibustion plays a unique advantage in the comprehensive treatment of tumors by regulating the levels of inflammatory factors such as IL-6, TNF - α, up regulating immune indicators such as CD4+/CD8+, improving the expression of neurotransmitters such as 5-HT, NE, etc., but there are still problems such as insufficient depth of mechanism analysis and lack of standardized schemes in the research.

Acupuncture and moxibustion therapy; Tumor supportive therapy; Neuroimmune regulation; Inflammatory microenvironment; Signal transduction