International Journal of Clinical Research

Objective Exploring the value analysis of blood routine indicators, scatter plots, and peripheral blood cell morphology in the diagnosis of acute leukemia. Methods 50 patients with acute leukemia who were first diagnosed in our hospital from January 2024 to January 2025 were selected as the observation group, and 50 healthy individuals who underwent physical examinations during the same period were selected as the control group. Comprehensive detection of blood routine indicators and changes in peripheral blood cell morphology, analyzing their clinical significance in early detection of acute leukemia. Results Among 50 cases of acute leukemia, the white blood cell levels in patients with acute promyelocytic leukemia were lower than those in the healthy control group (P<0.05), while the white blood cell counts in patients with other types of acute myeloid and acute lymphocytic leukemia were higher than those in the control group (P<0.05). Meanwhile, the red blood cell count, hemoglobin concentration, and platelet levels in all leukemia patient groups were significantly lower than those in the control group (P<0.05). According to the scatter plot alarm prompt provided by the blood routine instrument, a total of 45 primitive and immature cells were detected in the peripheral blood samples of these 50 patients, with a positive detection rate of 90%. Conclusion The combination of blood routine indicators, scatter plot analysis, and peripheral blood cell morphology examination has important value in early screening of acute leukemia, which helps to timely detect suspected cases in clinical practice and guide further examination.

Acute leukemia; Routine blood test; Scatter plot; Morphology of peripheral blood cells; Early screening