Journal of International Psychiatry

[Abstract] Objective To explore the relationship between the illness state uncertainty of ulcerative colitis and negative emotions such as anxiety and depression. Methods Eighty patients with ulcerative colitis in our hospital from February 2018 to February 2020 were selected as the study subjects. The Chinese version of the Mishel disease uncertainty questionnaire (MUIS) was used to evaluate the current status of patient’s illness state uncertainty. The differences between Hamilton depression scale (HAMD) and Hamilton Anxiety Scale (HAMA) in patients with different levels of illness state uncertainty were compared. Pearson correlation analysis were used to explore the correlation between MUIS score and HAMD and HAMA scores. Results The total MUIS score of 80 patients with ulcerative colitis was (58.93±6.87), 23 were low-level, 38 were medium-level, and 19 were high-level. The HAMD score and HAMA score of the high-level group of illness state uncertainty were significantly higher than those of the middle and low-level group, the middle-level group was significantly higher than the HAMD score, and the HAMA score was significantly higher than the low-level group, the difference was statistically significant (P<0.05). The complexity, uncertainty and total score of the MUIS scale for patients with ulcerative colitis were positively correlated with HAMD score and HAMA score (P<0.05). Conclusion Patients with ulcerative colitis generally have a sense of uncertainty in their illness, which is mainly at a moderate level, and has a significant correlation with negative emotions. Corresponding measures should be taken clinically to reduce the uncertainty of patients condition in order to improve negative emotions.