比较癫痫患者伴发抑郁后心理治疗和帕罗西汀治疗的疗效
Objective to compare the efficacy of psychotherapy and paroxetine in epilepsy patients with depression
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(6) |
| 作者 |
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| 作者单位 |
郑州人民医院 ;
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| 摘要 |
【摘要】目的：研究分析心理治疗与帕罗西汀对癫痫伴发抑郁患者的临床治疗效果。方法：将本院于2019年08月--2020年08月纳入的136例癫痫伴发抑郁患者作为观察对象。按照随机对照试验要求，将观察主体划分成对照的两个小组并分别命名为常规组（帕罗西汀）、研究组（帕罗西汀+心理治疗），各68例。结果：研究组总体疗效更高，与常规组之间存在明显差异（p<0.05）；研究组HAMD抑郁心理评分更低，与常规组之间存在明显差异（p<0.05）；研究组不良反应少于常规组（p<0.05）。结论：癫痫伴发患者应用帕罗西汀治疗的同时加强心理治疗，可获得更高的临床疗效，不仅可以减轻患者抑郁程度，而且还可以规避药物不良反应，安全性较高。
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| Abstract |
[Abstract] Objective: To study and analyze the clinical effect of psychotherapy and paroxetine on epilepsy patients with depression. Methods: 136 epileptic patients with depression in our hospital from August 2019 to August 2020 were selected as the observation objects. According to the requirements of randomized controlled trial, the observation subjects were divided into two control groups and named as the conventional group (paroxetine) and the study group (paroxetine + psychotherapy), 68 cases in each group. Results: the overall efficacy of the study group was higher than that of the conventional group (P < 0.05); the HAMD depression score of the study group was lower than that of the conventional group (P < 0.05); the adverse reactions of the study group were less than those of the conventional group (P < 0.05). Conclusion: the application of paroxetine in the treatment of patients with epilepsy can obtain higher clinical efficacy, not only can reduce the degree of depression, but also can avoid adverse drug reactions, with high safety.
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| 关键词 |
【关键词】帕罗西汀；心理治疗；癫痫；抑郁；疗效
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| KeyWord |
[Key words] paroxetine; psychotherapy; epilepsy; depression; curative effect
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| 基金项目 |
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| 页码 |
1145-1147 |
李艳艳*.
比较癫痫患者伴发抑郁后心理治疗和帕罗西汀治疗的疗效 [J].
国际精神病学杂志.
2020; 47; (6).
1145 - 1147.