棕榈酸帕利哌酮注射液治疗精神分裂症后患者依从性的影响因素研究

Study on the influencing factors of compliance in patients with schizophrenia treated with palmitone

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2022, 49(1)
作者
作者单位

上海市静安区精神卫生中心 ;
浙江省永康市第三人民医院 ;
浙江省衢州市第三医院 ;
浙江省金华市第二医院 ;

摘要
研究棕榈酸帕利哌酮注射液治疗精神分裂症后患者依从性的影响因素。方法 纳入2017年1月至2019年3月精神科收治的165例精神分裂症患者为研究对象。患者均采用棕榈酸帕利哌酮注射液治疗,收集患者各项临床基本资料,并进行为期1年随访,观察1年内棕榈酸帕利哌酮注射液治疗患者依从性情况,并采用多因素Logistic回归分析法分析棕榈酸帕利哌酮注射液治疗精神分裂症后患者依从性的独立影响因素。结果 1年随访期内,3例脱落,共162例患者获有效随访,其中102例患者坚持使用棕榈酸帕利哌酮注射液治疗,占62.96%;60例患者治疗中断,占37.04%。多因素Logistic回归分析显示,年龄(OR=1.431,95%CI=1.357~1.518)、家庭人均月收入(OR=3.257,95%CI=0.673~1.288)、第3针剂量(OR=1.554,95%CI=1.242~1.412)、自知力(OR=1.670,95%CI=1.515~1.678)是棕榈酸帕利哌酮注射液治疗精神分裂症后患者依从性的独立影响因素。结论 精神分裂症患者治疗依从性较差,年龄、家庭人均月收入、第3针剂量、自知力是棕榈酸帕利哌酮注射液治疗精神分裂症后患者依从性的独立影响因素。
Abstract
Objective To study the influence factors of compliance of patients with schizophrenia treated with palmitone.Methods 165 schizophrenics admitted to psychiatric from January 2017 to March 2019 were included in the study. All the patients were treated with palmitone palmitate injection. The basic clinical data of the patients were collected and followed up for one year. The compliance of the patients treated with palmitone palmitate injection was observed within one year. The independent influencing factors of the compliance of the patients treated with palmitone palmitate injection were analyzed by multivariate logistic regression analysis.Results During the 1-year follow-up period, 3 cases fell off and 162 cases were followed up effectively, 102 patients were treated with palmitone palmitate injection, accounting for 62.96%; 60 patients were interrupted, accounting for 37.04%.Multivariate logistic regression analysis showed that age(OR=1.431,95%CI=1.357~1.518), family per capita monthly income(OR=3.257,95%CI=0.673~1.288), dose of the third injection(OR=1.554,95%CI=1.242~1.412), self-knowledge(OR=1.670,95%CI=1.515~1.678)were independent factors influencing the compliance of patients with schizophrenia treated by palmitone injection.Conclusion The treatment compliance of schizophrenic patients was poor. Age, family per capita monthly income, dose of the third injection and self-knowledge were the independent influencing factors
关键词
棕榈酸帕利哌酮注射液;精神分裂症;依从性;影响因素
KeyWord
Palmitone palmitate injection; Schizophrenia; Compliance;influence factor
基金项目
页码 31-34
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张岩,钱雅雯,杨欧,郑达,罗晓东*. 棕榈酸帕利哌酮注射液治疗精神分裂症后患者依从性的影响因素研究 [J]. 国际精神病学杂志. 2022; 49; (1). 31 - 34.

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