Journal of Modern Nursing MedicineJPCNS

Objective To analyze and explore in depth the clinical efficacy of amiodarone in the treatment of emergency coronary heart disease patients with concomitant tachyarrhythmia, with the hope of effectively applying all research results to clinical practice, thereby promoting the development process of this field and better safeguarding the life and health of patients. Methods The study period was set from September 2023 to September 2024, and 90 patients with coronary heart disease and rapid arrhythmia admitted to the emergency department were included as the research subjects. Following the principle of "parallel sequential" grouping, the numerical table division method was used to implement group division, and each group was assigned (n=45), named as the reference group and the study group, respectively. The former adopts intravenous injection of lidocaine loading dose+maintenance dose treatment. The latter adopts intravenous injection of amiodarone loading dose+maintenance dose treatment, and finally collects and organizes relevant data, summarizes clinical data, evaluates and compares treatment effects. The comparison data includes: arrhythmia conversion rate, conversion time, improvement of cardiac function, and incidence of adverse reactions. Results After the completion of the experiment and statistical analysis, it was found that the study group showed significant improvement in left ventricular ejection fraction (LVEF), NYHA grading of cardiac function, and incidence of adverse reactions compared to the reference group, with a P value of<0.05, which is worth exploring. Conclusion For patients with coronary heart disease complicated by rapid arrhythmia, it is recommended to prioritize and adopt the implementation plan proposed by the research group in the horizontal selection of clinical treatment plans. This plan not only quickly and effectively restores the patients heart rhythm and significantly improves their cardiac function, but also demonstrates a high level of safety assurance. Overall, this treatment plan has significant advantages and is worthy of widespread promotion and application in emergency clinical practice, in order to benefit more patients and bring positive treatment outcomes.

Amiodarone; Emergency coronary heart disease; Rapid arrhythmia; Clinical efficacy