阿立哌唑联合舍曲林对精神分裂症合并抑郁患者的临床效果及有效率分析
Clinical effect and efficiency of aripiprazole combined with sertraline in the treatment of schizophrenia with depression
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2021, 48(5) |
| 作者 |
|
| 作者单位 |
许昌市建安医院精神科 ;
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| 摘要 |
【摘要】目的：探讨精神分裂症合并抑郁患者采用阿立哌唑治疗基础上联合舍曲林治疗的临床效果及有效率。方法：本文将2018年2月至2020年2月收治的精神分裂症合并抑郁患者110例作为研究对象，按照随机数字表法分组，对照组55例患者采用阿立哌唑治疗，观察组55例患者在对照组的基础上联合舍曲林治疗，统计分析治疗后有效率、治疗前后PANSS评分、HAMD评分、血清蛋白因子水平及不良反应发生情况。结果：两组之间治疗后有效率相比，观察组较对照组高；PANSS评分、HAMD评分、血清蛋白因子水平及不良反应发生情况相比，观察组较对照组低，P＜0.05。结论：采用阿立哌唑治疗精神分裂症合并抑郁的基础上联合舍曲林治疗可提升疗效，改善患者的抑郁症状，降低血清蛋白因子水平，提高用药安全性，进而有效改善患者预后。
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| Abstract |
[Abstract] Objective: To investigate the clinical effect and efficiency of sertraline combined with aripiprazole in the treatment of schizophrenia with depression. Methods: 110 schizophrenic patients with depression from February 2018 to February 2020 were randomly divided into two groups. 55 patients in the control group were treated with aripiprazole, and 55 patients in the observation group were treated with sertraline on the basis of the control group. The effective rate after treatment, PANSS score before and after treatment, HAMD score and serum protein factor were statistically analyzed Sub level and adverse reactions. Results: after treatment, the effective rate of the observation group was higher than that of the control group; PANSS score, HAMD score, serum protein factor level and adverse reactions of the observation group were lower than those of the control group, P < 0.05. Conclusion: aripiprazole combined with sertraline in the treatment of schizophrenia with depression can improve the curative effect, improve the depressive symptoms, reduce the level of serum protein factor, improve the safety of medication, and then effectively improve the prognosis of patients.
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| 关键词 |
关键词：精神分裂症；抑郁；舍曲林；阿立哌唑；临床效果；有效率
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| KeyWord |
Key words: Schizophrenia; depression; sertraline; aripiprazole; clinical effect; effective rate
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| 基金项目 |
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| 页码 |
819-821 |
孙秋云*.
阿立哌唑联合舍曲林对精神分裂症合并抑郁患者的临床效果及有效率分析 [J].
国际精神病学杂志.
2021; 48; (5).
819 - 821.