某院2014年300例患者复方参芪维E胶囊药物使用合理性评价

Evaluation on rationality of drug use of compound Shenqiwei E capsule for 300 patients in a hospital in 2014

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DOI 10.12208/j.ijmd.20250047
刊名
International Journal of Medicine and Data
年,卷(期) 2025, 9(2)
作者
作者单位

川北医学院附属医院 四川南充

摘要
目的 针对复方参芪维E胶囊在儿童、孕妇及老年人群中的用药安全性问题,系统分析其药物相互作用特征及用药合理性,为特殊人群的临床用药提供参考。方法 采用回顾性调查方法,纳入2013年6月至2015年4月期间使用该药的住院及门诊患者共300例,按照相关诊疗规范评价用药合理性,评估药物相互作用及药物过量的风险。结果 300例患者中,用药完全合理者占56.0%,不合理用药发生率为29.3%;主要不合理类型为用法用量不当(16.0%)和适应症不符(44.3%)。儿童、孕妇和老人由于身体机能和代谢特点与普通成年人存在较大差异,对药物的反应也更为复杂,用药安全性和有效性的评估需要更加谨慎。结论 尽管复方参芪维E胶囊在多数患者中展现出了良好的耐受性和有效性,但为了确保该药品在临床使用中的安全性,尤其是在上述特殊人群及特殊用药情况下,仍需进一步补充相关研究情况,开展更深入的研究。
Abstract
Objective In view of the safety of compound Shenqiwei E capsule in children, pregnant women and the elderly, the characteristics of drug interaction and the rationality of drug use were systematically analyzed, so as to provide reference for clinical drug use of special people. Methods A total of 300 inpatients and outpatients who used the drug from June 2013 to April 2015 were included by retrospective investigation. The rationality of drug use was evaluated according to the relevant diagnosis and treatment norms, and the risk of drug interaction and drug overdose was evaluated. Results Among the 300 patients, 56.0% were completely rational, and the incidence of irrational drug use was 29.3%. The main unreasonable types are improper usage and dosage (16.0%) and inconsistent indications (44.3%). Children, pregnant women and the elderly are quite different from ordinary adults because of their physical function and metabolic characteristics, and their reactions to drugs are more complicated, so the evaluation of drug safety and effectiveness needs to be more cautious. Conclusion Although compound Shenqiwei E capsule has shown good tolerance and effectiveness in most patients, in order to ensure the safety of the drug in clinical use, especially in the above-mentioned special population and special drug use, it is still necessary to further supplement the relevant research and carry out more in-depth research.
关键词
复方参芪维E胶囊药物;儿童;孕妇;老人;药物相互作用
KeyWord
Compound Shenqiwei E capsule drug; Children; Pregnant women; Old people; Drug interaction
基金项目
页码 126-126
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任红伍*. 某院2014年300例患者复方参芪维E胶囊药物使用合理性评价 [J]. 国际医学与数据杂志. 2025; 9; (2). 126 - 126.

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