Journal of International Psychiatry

Schizophrenia occurs in young adults. Most patients have poor drug compliance, leading to repeated symptoms, prolonged course of disease, and continuous decline of social function. The long-term injection of paliperidone palmitate can improve the compliance of patients with long-term treatment, reduce recurrence and readmission rates, and improve their social functions. Its clinical efficacy and cost-effectiveness are superior to most oral antipsychotics. Under the hospital community integrated management mode, the advantages of palmitate paliperidone are further revealed. The purpose of this review is to discuss the recurrence rate, safety, cost-effectiveness of palmitate long-acting injection in the treatment of schizophrenia and the importance of its application in the hospital community integrated management model.

Schizophrenia; Palmitate paliperidone; Recurrence rates; Cost-effectiveness; The hospital community integrated management model