| Abstract |
【Abstract】 Objective To explore the value of transcranial magnetic stimulation (rTMS) as an adjuvant therapy for impulsive and aggressive behavior in schizophrenia and its impact on serum prolactin (PRL) levels. 【Methods】 A total of 106 patients with schizophrenia and impulsive and aggressive behavior admitted to our hospital from January 2021 to February 2023 were selected. They were randomly divided into an observation group and a control group using a random number table method, with 53 patients in each group. The observation group received true (low-frequency) rTMS treatment, while the control group received false rTMS treatment. Compare two sets of positive and negative symptom scales (PANSS), and evaluate two sets of explicit aggressive behavior scales (MOAS), concise psychiatric assessment scales (BPRS), and detect serum PRL levels.【Results】 The results showed that the positive factor score, negative factor score, general psychopathological score, and total score of the observation group were significantly lower than those of the control group after treatment, with a statistically significant difference (P<0.05); After treatment, the MOAS and BPRS scores in the observation group were significantly lower than those in the control group, with a statistically significant difference (P<0.05);After treatment, the serum PRL level in the observation group (67.45 ± 4.41) was significantly lower than that in the control group (71.45 ± 5.21), with a statistically significant difference (t=4.266, P=0.000) 【Conclusion】 rTMS assisted treatment of impulsive and aggressive behavior in schizophrenia can not only effectively improve positive and negative symptoms, aggressive behavior, and mental symptoms, but also improve serum PRL levels, which is safe.
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