Journal of International Psychiatry

【Abstract】Objective To explore whether computerized cognitive remediation therapy has any improvement effect on cognitive function in male schizophrenia patients. Methods Eighty-seven stable male patients with schizophrenia were included and randomly divided into the observation group (CCRT+antipsychotic medication, 45 patients) and the control group (single antipsychotic treatment, 42 patients), and the cognitive function of the patients was assessed by the C-BCT at the baseline and at the end of the rehabilitation training and their psychiatric symptoms were assessed by the PANSS. Results The differences in general demographic information and PANSS total score scores between the control group and the observation group at baseline were not statistically significant (p>0.05), the differences between the patients of the observation group after CCRT rehabilitation training in satellite exploration, speed matching, color stroop, and before and after changes in Lost Fish were statistically significant (p<0.05), and the differences in dual visual memory and speed classification were not statistically significant (p>0.05). 0.05), the cognitive function of the observation group after CCRT rehabilitation training compared with the control group, in which the differences in total T-score, connectivity T-score, and sustained operation T-score were statistically significant (p<0.05), while the differences in digit breadth T-score, and symbol encoding T-score were not statistically significant (p>0.05) Conclusion CCRT rehabilitation training combined with antipsychotic medication is more effective than a single antipsychotic medication to improve cognitive function in male schizophrenic patients.

schizophrenia; cognitive function; computerized remediation therapy