老年精神分裂症患者复发的影响因素及其与营养状况的相关性分析

Analysis of factors influencing relapse in elderly patients with schizophrenia and its correlation with nutritional status

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2024, 51(4)
作者
作者单位

成都市第四人民医院后勤保障部 ;

摘要
【摘要】分析老年期精神分裂症患者复发的影响因素及其与营养状况的相关性。方法 回顾性分析2022年1月~2022年12月在我院进行治疗的130例老年期精神分裂症患者的临床资料,对所有患者进行1年随访,依据简明精神病评定量表(Brief Psychiatric Rating Scale,BPRS)结果将其分为复发组(n=43)、未复发组(n=87)。比较两组基线资料、及入院时营养风险筛查2002评分(Nutrition Risk Screening2002,NRS2002)、微型营养评定法(mini-nutritional assessment,MNA)评分。采用多因素Logistic回归分析老年期精神分裂症复发的影响因素。结果 复发组身体质量指数(body mass index,BMI)<25kg/m2、病程≥5年、家族史阳性、服药不依从、NRS2002≥3分、MNA<24分的占比均高于未复发组(P<0.05);经多因素Logistic回归分析证实,BMI<25kg/m2、病程≥5年、家族史阳性、服药不依从、NRS2002≥3分、MNA<24分均为老年期精神分裂症复发的危险因素,均有P<0.05。结论 患者BMI、病程、家族史、服药依从性及营养状况均为患者复发的影响因素,营养不良将增加患者复发风险,应对营养失衡患者给予重点关注,及时采取干预措施,减少复发可能性。
Abstract
【Abstract】Objective The influence factors of relapse in elderly patients with schizophrenia and its correlation with nutritional status. Methods Retrospective analysis from January 2022 to December 2022 in our hospital for treatment of the clinical data of 130 cases of elderly patients with schizophrenia, with 1 year follow-up of all patients, based on the Brief Psychiatric Rating Scale (Brief informed Rating Scale,Results They were divided into relapse group (n=43) and non-relapse group (n=87).Nutritional Risk Screening2002 (NRS2002) and mini-nutritional assessment (MNA) scores were compared between the two groups.Multivariate Logistic regression was used to analyze the influencing factors of relapse in elderly schizophrenia. Results The proportion of body mass index (BMI) < 25kg/m2, disease course ≥5 years, positive family history, drug noncompliance, NRS2002≥3 points, MNA < 24 points in relapse group was higher than that in non-relapse group (P < 0.05). Multivariate Logistic regression analysis confirmed that BMI < 25kg/m2, duration ≥5 years, positive family history, non-compliance, NRS2002≥3 points, MNA < 24 points were all risk factors for relapse of elderly schizophrenia, all with P < 0.05.Conclusion The BMI, duration, family history, medication adherence and nutrition are the influence factors of patients with recurrence, patients with malnutrition will increase the risk of recurrence, should focus on the patients with nutritional imbalance, take timely intervention measures to reduce the possibility of recurrence.
关键词
【关键词】老年期精神分裂症;营养状况;复发;微型营养评定法;营养风险筛查2002评分
KeyWord
【Key words】Senile schizophrenia; Nutritional status; Recurrence; Mini-nutritional assessment; Nutritional Risk Screening 2002 score
基金项目
页码 1057-1060
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王威*. 老年精神分裂症患者复发的影响因素及其与营养状况的相关性分析 [J]. 国际精神病学杂志. 2024; 51; (4). 1057 - 1060.

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