氘丁苯那嗪治疗迟发性运动障碍一例

A case of Deutetrabenazine in the treatment of tardive dyskinesia

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2024, 51(4)
作者
作者单位

山西医科大学附属精神卫生医院 ;

摘要
迟发性运动障碍(tardive dyskinesia,TD)是一种严重影响患者日常生活能力的疾病,是精神科药物使用过程中常见的不良反应。自2017年氘丁苯那嗪被批准用于治疗TD后,该药逐渐在临床上使用,循证证据提示该药的疗效及耐受性良好。本例患者为66岁女性,诊断“抑郁障碍”,长期服用多塞平片及奋乃静片,逐渐出现四肢发麻伴不自主抽动、口唇蠕动等症状,诊断“TD”,给予维生素C、氯硝西泮等药物对症治疗效果欠佳,后口服氘丁苯那嗪片症状逐渐减轻,治疗效果好。本文通过对该病例的报道,以期为精神科的临床工作提供参考和经验。
Abstract
Tardive dyskinesia(TD) is a disease that can seriously influence the living ability of patients. It’s a common adverse effect in the procedure of psychiatry dose take medicine. Since deutetrabenazine was used to cure tardive dyskinesia in 2017, this medicine was gradually used in clinical treatment. Conformation evidence gives a cue that this medicine has a good therapeutic effect and tolerance. This patient is a woman aged 66 who is diagnosed with “depressive disorder”. She has taken doxepin and perphenazine tablets for a long time and has the symptoms of numbness of limbs, involuntary twitch, and oral peristalsis. She was diagnosed as “TD” and had a bad effect after she took vitamin C and clonazepam. Later she had a good effect after taking deutetrabenazine tablets and the symptom was gradually worsening. This article will be used to provide reference and experience in the clinical work of psychiatry through this case report.
关键词
运动障碍;迟发性运动障碍;氘丁苯那嗪;抗精神病药;
KeyWord
Movement disorders; Tardive Dyskinesia;Deutetrabenazine; Antipsychotic Agents;
基金项目
页码 1342-1344
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焦志鹏,王丽,阎丹峰,王斌红*. 氘丁苯那嗪治疗迟发性运动障碍一例 [J]. 国际精神病学杂志. 2024; 51; (4). 1342 - 1344.

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