文拉法辛对产后抑郁患者负面情绪、睡眠及认知功能的影响分析
Effect of venlafaxine on negative emotion, sleep and cognitive function in patients with postpartum depression
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2024, 51(5) |
| 作者 |
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| 作者单位 |
海南省安宁医院 药剂科 ;
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| 摘要 |
【摘要】目的：探讨产后抑郁患者病情控制中，采用文拉法辛的价值，并分析该方案对负面情绪、睡眠及认知功能的影响。方法：由研究人员采用EXCEL表格统计2021年1月~2022年12月这一时间范围内，在我院通过相关检查由医师确诊为产后抑郁的80例患者，按照随机数字表法分为2组，40例纳入对照组实施帕罗西汀治疗，40例纳入观察组实施文拉法辛治疗。统计治疗后临床疗效，并就治疗前后患者负面情绪、睡眠状态、认知功能等进行评价。结果：观察组40例患者经文拉法辛治疗后，记录的临床疗效为97.50%，较对照组升高（P<0.05）；观察组记录的爱丁堡产后抑郁量表（EPDS）评分（4.22±0.21）分低于对照组（P<0.05）；观察组记录的匹兹堡睡眠质量指数（PSQI）评分低于对照组（P<0.05）；观察组记录的蒙特利尔认知评估量表(MoCA)评分高于对照组（P<0.05）。结论：在产后抑郁患者的治疗过程中，选择文拉法辛可明显改善患者抑郁状态，同时可促进其睡眠及认知功能恢复。
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| Abstract |
[Abstract] Objective: To explore the value of venlafaxine in the control of postpartum depression, and analyze the impact of this program on negative emotion, sleep and cognitive function. Methods: The researchers used EXCEL form to count 80 patients who were diagnosed as postpartum depression by doctors through relevant examinations in our hospital from January 2021 to December 2022. They were divided into two groups according to the random number table. 40 patients were included in the control group to receive paroxetine treatment, and 40 patients were included in the observation group to receive venlafaxine treatment. Calculate the clinical efficacy after treatment and evaluate the patients negative emotions, sleep status, cognitive function, etc. before and after treatment. Results: 40 patients in the observation group were treated with venlafaxine, and the recorded clinical efficacy was 97.50%, higher than that in the control group (P<0.05); The EPDS score recorded in the observation group (4.22 ± 0.21) was lower than that in the control group (P<0.05); The PSQI score recorded in the observation group was lower than that in the control group (P<0.05); The MoCA score recorded in the observation group was higher than that in the control group (P<0.05). Conclusion: During the treatment of postpartum depression, venlafaxine can significantly improve the depressive state of patients, and promote their sleep and cognitive function recovery.
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| 关键词 |
关键词：文拉法辛；产后抑郁；负面情绪；睡眠；认知功能
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| KeyWord |
Key words: venlafaxine; Postpartum depression; Negative emotions; Sleep; cognitive function
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| 基金项目 |
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| 页码 |
1536-1538 |
程丹*.
文拉法辛对产后抑郁患者负面情绪、睡眠及认知功能的影响分析 [J].
国际精神病学杂志.
2024; 51; (5).
1536 - 1538.