International Journal of Clinical Research

Objective To study and analyze the clinical efficacy of amiodarone in the treatment of tachyarrhythmias in emergency coronary heart disease. Methods A total of 105 patients with tachyarrhythmias in coronary heart disease who were treated in the emergency department of our hospital from October 2023 to October 2024 were selected as the research subjects and randomly divided into the experimental group (55 cases) and the reference group (50 cases). They were treated with amiodarone and propafenone respectively, and the treatment efficacy, cardiac function index levels and quality of life were compared. Results (1) After comparison, the clinical treatment efficacy of the experimental group was significantly higher, and the data were statistically significant (P < 0.05); (2) After treatment, the left ventricular end-diastolic diameter (LVEDD) and left ventricular end-systolic diameter (LVESD) of the experimental group were significantly lower than those of the reference group, and the left ventricular ejection fraction (LVEF) and cardiac output (CO) of the experimental group were significantly higher than those of the reference group, and the data were statistically significant (P < 0.05); (3) After treatment, the quality of life score of the experimental group was significantly higher than that of the reference group, and the data were statistically significant (P < 0.05). Conclusion The application of amiodarone in the treatment of emergency coronary heart disease with tachyarrhythmia has significant clinical effect, which can not only significantly improve the patients cardiac function, but also significantly improve the patients quality of life, and is worthy of promotion.

Amiodarone; propafenone; Coronary heart disease; Tachyarrhythmia; Cardiac function; Quality of life