International Journal of Clinical Research

Objective To study the effect and value of oral care solution with different concentrations of chlorhexidine in intensive care unit patients. Methods A total of 84 patients were enrolled in this study, all of whom were from intensive care units in our hospital from December 2022 to December 2023. They were divided into four groups according to the odd and even random principle: normal saline group, 0.12% chlorhexidine group, 0.20% chlorhexidine group and 2.00% chlorhexidine group. Oral scores, positive detection rate of oral flora and incidence of pneumonia were evaluated and analyzed. Results After intervention, the value of OAG score and positive detection rate of oral bacteria including Klebsiella pneumoniae, Staphylococcus aureus, hemolytic streptococcus, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii before and after care among the four groups was P < 0.05, indicating comparative significance. The incidence of pneumonia among the four groups was P>0.05, indicating that there was no comparative significance. Conclusion The application of different concentrations of chlorhexidine oral care solution in the nursing work of patients in intensive care unit has a positive effect on the improvement of the oral environment of patients in intensive care unit, and has a certain inhibitory effect on the occurrence of pneumonia, which is worthy of clinical promotion.

Different concentration; Chlorhexidine; Oral care; Intensive care unit; Pneumonia; Oral flora