International Journal of Clinical Research

Objective To analyze the therapeutic effects of aspirin and clopidogrel on elderly patients with coronary heart disease. Methods 80 elderly patients with coronary heart disease who visited our hospital from March 2021 to March 2023 were randomly divided into a control group of 40 cases using a stratified random method and treated with aspirin. The other 40 cases were treated with clopidogrel in addition to aspirin in the observation group. The anticoagulant effect, platelet function, and incidence of adverse reactions were compared between the two groups before and after treatment; Results Before treatment, there was no significant difference in anticoagulant indicators and platelet function between the two groups, P>0.05. After treatment, the indicators of the observation group were better than those of the control group, with a significant difference, P<0.05. There was no significant difference in the incidence of adverse reactions between the two groups, P>0.05. Conclusion The use of aspirin and clopidogrel in the treatment of elderly patients with coronary heart disease has a good effect, high safety, and significant efficacy. It can reduce platelet aggregation, prevent thrombotic diseases, and delay disease progression.

Aspirin; Clopidogrel; Elderly coronary heart disease; Therapeutic effect; Security