International Journal of Clinical Research

Objective To analyze general anesthesia, dexmedetomidine combined with Orididine fumarate was used for anesthesia management to stabilize the hemodynamic index. Methods 100 patients under general anesthesia from January 20232 to December 2023 were selected with sufentanil in the control group; dexmedetomidine and fumarate were used in the observation group to compare the clinical nursing effect. Results There was no significant difference in extubation time, recovery time and consciousness recovery time in the control group (P> 0.05). However, after T2, T3 and T4, the heart rate and blood pressure of the observation group were lower than that of the control group (P <0.05); moreover, in the Ramsay sedation score of the comparison patients, the differences between the 1 hour, 6 hours and 12 hours after the observation group were significant, and in the MMSE score, the total score of the observation group was higher than that of the control group, and the comparison difference was significant (P <0.05). Finally, the incidence of adverse reactions in patients varied greatly (P <0.05). Conclusion Patients with general anesthesia use dexmedetomidine, and the effect of fumarate is remarkable, which helps to stabilize the hemodynamic indicators, play the analgesic effect, and prevent the agitation of patients in the awakening period, reduce the incidence of postoperative nausea and vomiting, and prevent the occurrence of adverse reactions, which is worth promoting.

Dexmedetomidine; Fumarate; Analgesic cohesion; General anesthesia; Awakening mass; Hemodyna-mics, Incidence of nausea and vomiting