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[Abstract] Objective To investigate the relationship between cognitive impairment (MCI) and white matter ischemic lesions in hypertensive intracerebral hemorrhage (HCH). Methods A total of 100 HCH patients in our hospital from February 2020 to February 2022 were selected as the study subjects. The Montreal Cognitive Assessment (MoCA) scale were used to assess patient MCI, and they were set as the MCI group and non-MCI group. The medical records such as gender, age, and degree of neurological dysfunction between the two groups of patients were compared. The MRI examination were used to evaluate degree, location and score of white matter ischemic lesions. Univariate and multivariate analysis of the relationship between HCH MCI and medical records and white matter ischemic lesions. Results Forty-five cases of MCI in 100 HCH patients. There were difference between MCI group and non-MCI group in terms of age, years of education, Barthel Index (MBI), National Institutes of Health Stroke Scale (NIHSS), hematoma volume, homocysteine (hcy) level and other medical records (P<0.05). There was no significant difference in gender and body mass index between the two groups (P>0.05). There were statistically significant differences in the score, location and severity of white matter ischemic lesions between the MCI group and the non-MCI group (P<0.05). Binary Logistic regression analysis showed that age, MBI score, NIHSS score, hematoma volume, hcy level, grade 3 white matter ischemic lesions, periventricular lesions, and severe lesions were independent risk factors for HCH MCI. Conclusion The higher incidence of MCI in HCH patients is related to motor function, neurological function, and white matter ischemic lesions.
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