Journal of International Psychiatry

Abstract Objective: To compare the efficacy of electroconvulsive therapy in adolescents and adults with depression, and to explore the related factors affecting electroconvulsive therapy. Methods: From August 2019 to January 2022, 19 adolescent depressive disorder patients and 28 adult depressive disorder patients who met the inclusion criteria in our hospital were enrolled. The two groups of patients were treated with electroconvulsive therapy, and the treatment effects were evaluated with Hamilton Depression Scale (HAMD) and Beck Suicidal Ideation Scale (BSI) before the first treatment and 24 hours after the end of the last treatment. Results:The adolescent group had more female patients, more common psychiatric symptoms, younger age, earlier onset, longer duration of depressive episodes, and fewer psychiatric hospitalizations, with statistically significant differences（P＜0.05）. After treatment, the HAMD and BSI scores of the two groups were significantly decreased (P＜0.05). There was no significant difference in the reduction rate of the scale scores between the two groups after treatment (P>0.05). Without non-suicidal self-injury behaviors (OR=9.500, 95%CI: 1.091-82.725), males (OR=7.467, 95%CI: 1.799-30.994) were associated with the efficacy of electroconvulsive therapy. Conclusion: Electroconvulsive therapy can significantly improve clinical symptoms and suicide risk in adolescent patients with depressive disorder and adults with depressive disorder. Without non-suicidal self-injury behavior and male gender are the influencing factors of effective electroconvulsive therapy.

Depression; Electroconvulsive therapy; Adolescent; Efficacy