西酞普兰、运动疗法联合人际心理治疗心肌梗死合并心理障碍患者的效果
Citalopram, exercise therapy combined with interpersonal psychotherapy Effect of myocardial infarction with psychological disorders
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2023, 50(4) |
| 作者 |
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| 作者单位 |
鹤壁市人民医院心血管内科 ;
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| 摘要 |
【摘要】探究西酞普兰、运动疗法联合人际心理治疗心肌梗死合并心理障碍患者的效果。方法 选取于2021年2月-2022年6月收治入我院的108例心肌梗死合并心理障碍患者作为研究对象，根据随机数字表法将其分为对照组和试验组，各54例。对照组患者接受常规护理+运动疗法+心理治疗，试验组患者在对照组的基础上增加西酞普兰治疗。对比组间患者负面情绪、心功能以及心率波动性（Heart rate variability，HRV)。结果 治疗前，组间患者负面情绪情况[抑郁自评量表（Self-rating depression scale，SDS）与焦虑自评量表（Self-rating anxiety scale，SAS）评分]对比，差异无统计学意义（P>0.05）；治疗3mo、6mo后，组间患者SDS与SAS评分均下降，且试验组显著低于对照组（P<0.05）。治疗前，组间患者心功能情况[左心室舒张期末内径（Left ventricular end-diastolic diameter，LVEDD）、左心室射血分数（left ventricular ejection fraction，LVEF)以及左心室收缩末期内径（Left ventricular end-systolic diameter，LVESD）水平]对比，差异无统计学意义（P>0.05）；治疗6mo后，组间LVEF水平均上升，且试验组LVEF水平显著高于对照组（P<0.05），组间LVEDD与LVESD水平均下降，且试验组LVEDD与LVESD水平显著低于对照组（P<0.05）。治疗6mo后，试验组患者HRV[24 h相邻R-R间期之差的均方根值(Root mean square successive difference，rMSSD)、正常R-R间期标准差（Standard deviation of normal-to-normal intervals，SDNN）、24h每5分钟窦性R-R间期均值标准差平均值（Mean of standard deviation of intervals for five minutes，SDNNi）以及5分钟窦性R-R间期均值标准差（Standard deviation of the five-minute mean cycle lengths，SDANN）]水平均明显高于对照组（P<0.05）。结论 西酞普兰、运动疗法联合人际心理应用于心肌梗死合并心理障碍，有助于降低患者抑郁、焦虑等负性情绪，促进改善患者HRV与心功能水平。
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| Abstract |
[Abstract] Objective To explore the effect of citalopram, exercise therapy and interpersonal psychology on patients with myocardial infarction and psychological disorders. Methods 108 patients with myocardial infarction and psychological disorders admitted to our hospital from February 2021 to June 2022 were selected as the study subjects. They were divided into control group and test group according to the random number table method, with 54 patients in each group. The patients in the control group received routine nursing+exercise therapy+psychotherapy, and the patients in the test group received citalopram treatment on the basis of the control group. Negative mood, heart function and heart rate variability (HRV) of patients in the control group were compared. Results Before treatment, there was no statistically significant difference in the negative mood between the two groups (SDS and SAS); After 3 and 6 months of treatment, the SDS and SAS scores of patients in the test group were significantly lower than those in the control group (P<0.05). Before treatment, there was no statistically significant difference in cardiac function between the groups (left ventricular end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF) and left ventricular end-systolic diameter (LVESD)); After 6 months of treatment, the level of LVEF in the test group was significantly higher than that in the control group (P<0.05), and the level of LVEDD and LVESD in the test group was significantly lower than that in the control group (P<0.05). After 6 months of treatment, HRV of patients in the test group [24 h root mean square successful difference (rMSSD), standard deviation of normal to normal intervals (SDNN), mean of standard deviation of interval for five minutes (SDNNi), and mean of standard deviation of interval for five minutes (SDNNi) of sinus R-R interval (Standard deviation of the five-minute mean cycle length, SDANN)] levels were significantly higher than those of the control group (P<0.05). Conclusion The application of citalopram, exercise therapy and interpersonal psychology in patients with myocardial infarction complicated with psychological disorders can help to reduce the negative emotions such as depression and anxiety, and promote the improvement of HRV and cardiac function.
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| 关键词 |
【关键词】西酞普兰；心肌梗死；心理障碍；左心室射血分数；抑郁自评量表
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| KeyWord |
[Key words] citalopram; miocardial infarction; Mental disorders; Left ventricular ejection fraction; Self-rating depression scale
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| 基金项目 |
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| 页码 |
802-805 |
秦英华*.
西酞普兰、运动疗法联合人际心理治疗心肌梗死合并心理障碍患者的效果 [J].
国际精神病学杂志.
2023; 50; (4).
802 - 805.