| Abstract |
[Abstract] Objective To explore the relationship between polysomnography (PSG) sleep parameters and cognitive impairment in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods A total of 114 OSAHS patients from June 2021 to January 2023 were selected as the study subjects, all of whom underwent polysomnography (PSG) monitoring. The Simplified Mental State Scale (MMSE) were used to Screen the cognitive impairment (CI). They were set as the CI group and the non CI group. The correlation between various parameters of PSG and MMSE scores of CI patients were analyzed. Results There were 28 cases of CI in 114 OSAHS patients, of which 24 were mild and 4 were moderate. The apnea hypopnea index (AHI), longest apnea time, hypopnea index, oxygen deficit index (ODI), and phase 2 sleep in the CI group were significantly higher than those in the non CI group. The mean arterial oxygen saturation (MSaO2), the lowest SaO2 (LSaO2), and the third stage sleep in the CI group were significantly lower than those in the non CI group (P<0.05). There was no statistically significant difference between the two groups in phase 1 sleep and rapid eye movement sleep (P>0.05). There was a negative correlation between AHI, longest apnea time, hypoventilation index, ODI, phase 2 sleep, and MMSE score in the CI group, while there was a positive correlation between MSaO2, LSaO2, and MMSE score (P<0.05). There was no significant correlation between phase 3 sleep, phase 1 sleep, and rapid eye movement sleep and MMSE score (P>0.05). Conclusion There is a significant correlation between OSAHS PSG sleep parameters and cognitive impairment, mainly manifested in increased shallow sleep time, repeated respiratory pauses, hypoventilation, and hypoxia.
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