干眼症患者眼表状态与睡眠质量及心理状态的相关性

Correlation between ocular surface status and sleep quality and mental state of patients with dry eye

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2023, 50(5)
作者
作者单位

首都医科大学石景山教学医院北京市石景山医院眼科 ;

摘要
摘要:目的:评估干眼症患者睡眠质量及焦虑、抑郁状态,并分析其与眼表状态的相关性。方法:选取干眼症患者98例作为研究组,另选同期健康体检者45例为对照组。采用匹兹堡睡眠质量指数(PSQI)评估睡眠状况,采用焦虑自评量表(SAS)、抑郁自评量表(SDS)评估焦虑和抑郁状态,采用眼表疾病指数(OSDI)量表评估眼表症状,采用眼表综合分析仪测量泪膜破裂时间(FBUT)、角膜染色评分(CFS)和基础泪液分泌试验(SⅠT)。比较两组上述指标,并分析眼表状态指标与PSQI、SAS、SDS评分的相关性。结果:研究组PSQI评分、SAS评分、SDS评分均高于对照组(P<0.05)。研究组OSDI评分、CFS评分均高于对照组,FBUT、SⅠT值均低于对照组(P<0.05)。Pearson相关性分析显示:OSDI、CFS评分与PSQI、SAS、SDS评分均呈正相关(P<0.05),FBUT、SⅠT值与PSQI、SAS、SDS评分均呈负相关(P<0.05)。结论:干眼症患者眼表状态与睡眠质量和焦虑、抑郁状态存在相关性,泪液分泌量、泪膜稳定性降低和角膜损伤等可能加重患者睡眠障碍和心理负担。
Abstract
Abstract: Objective: To evaluate the sleep quality, anxiety and depression status of patients with dry eye, and analyze their correlation with ocular surface status. Methods: 98 patients with dry eye were selected as the research group, and another 45 healthy individuals were selected as the control group. The PSQI was used to assess sleep status, the SAS and SDS were used to assess anxiety and depression status, the OSDI was used to assess eye surface symptoms, and FBUT, CFS, SIT were measured using an eye surface comprehensive analyzer. Analyze the correlation between eye surface status indicators and PSQI, SAS, SDS scores. Result: The PSQI, SAS and SDS scores of the study group were higher than those of the control group (P<0.05). The OSDI, CFS scores of the study group were higher than those of the control group, while the FBUT, SIT values were lower than those of the control group (P<0.05). The OSDI and CFS scores were positively correlated with PSQI, SAS, and SDS scores (P<0.05), the FBUT, SIT values were negatively correlated with PSQI, SAS, and SDS scores (P<0.05). Conclusion: There is a correlation between the ocular surface state and sleep quality, mental state in patients with dry eye syndrome; Decreased tear secretion, decreased tear film stability, and corneal damage may exacerbate sleep disorders and psychological burden in patients.
关键词
【关键词】干眼症;眼表状态;睡眠质量;焦虑;抑郁
KeyWord
Key words: Dry eye syndrome; Ocular surface status; Sleep quality; Anxiety; Depression
基金项目
页码 1151-1154
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李晓月*. 干眼症患者眼表状态与睡眠质量及心理状态的相关性 [J]. 国际精神病学杂志. 2023; 50; (5). 1151 - 1154.

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