系统性红斑狼疮患者伴发抑郁障碍的研究进展

系统性红斑狼疮(SLE)伴发抑郁障碍对SLE患者身心健康的影响全面而持久,目前SLE伴发抑郁障碍的早期诊断存在困难,治疗不够规范。本文回顾了SLE患者伴发抑郁障碍的流行病学特征、临床评估,归纳了SLE疾病相关因素对抑郁情绪的影响,抑郁情绪对疾病发生发展的干扰,认为临床上需要重视SLE患者抑郁症状的筛查,治疗上避免类固醇使用引发的抑郁相关副作用,并介绍了新冠肺炎疫情对SLE病情的影响。

ES评分 0

DOI
刊名
Journal of International Psychiatry
年,卷(期) 2023, 50(5)
作者
作者单位

南京医科大学附属无锡市精神卫生中心 ;
江南大学附属医院 ;

摘要
系统性红斑狼疮(SLE)伴发抑郁障碍对SLE患者身心健康的影响全面而持久,目前SLE伴发抑郁障碍的早期诊断存在困难,治疗不够规范。本文回顾了SLE患者伴发抑郁障碍的流行病学特征、临床评估,归纳了SLE疾病相关因素对抑郁情绪的影响,抑郁情绪对疾病发生发展的干扰,认为临床上需要重视SLE患者抑郁症状的筛查,治疗上避免类固醇使用引发的抑郁相关副作用,并介绍了新冠肺炎疫情对SLE病情的影响。
Abstract
Depression in patients with systemic lupus erythematosus (SLE) has a comprehensive and lasting impact on the physical and mental health of SLE patients. At present, the early diagnosis of SLE with depression is difficult and the treatment is not standardized. This article reviews the epidemiological characteristics and clinical evaluation of SLE patients with depressive disorder, summarizes the effects of SLE related factors on depression, and the interference of depression on the development of disease. It is considered that clinical attention should be paid to the screening of depressive symptoms in patients with SLE, and the side effects of depression induced by steroid use should be avoided. New changes in COVID-19 are introduced. This paper reviews the related studies of SLE patients with depression.
关键词
系统性红斑狼疮;抑郁障碍;抗核糖体P蛋白;糖皮质激素;新型冠状病毒肺炎
KeyWord
Systemic lupus erythematosus;depression; Anti-ribosomal P protein antibodies;Corticosteroids; COVID-19
基金项目
页码 939-941
  • 参考文献
  • 相关文献
  • 引用本文

高学正,刘敏黎,李达,周振和*. 系统性红斑狼疮患者伴发抑郁障碍的研究进展 [J]. 国际精神病学杂志. 2023; 50; (5). 939 - 941.

  • 文献评论

相关学者

相关机构